Part 1: sought to give the reader a general understanding of oxidative stress, and the importance of anti inflammatory’s for a robust immune, neuro, endocrine system(s), along with the host microbiota.
Let me keep you all again to the molecular level, and introduce you all to your genetic best friend: your Telomere. Telomere (singular) pronounced, tee-lo-mere, is a book on it’s own! (1). However analogously think of your telomere as your protective cap at the end of your shoelace, a neat analogy indeed. Why so? in order for genetic material to be replicated (mRNA). Your genetic best friend, plays an important role in maintaining the length of your telomere, so, cell division can take place, and your shoelace remains rancid free. Now, the aforementioned is a very simple explanation, without going into nucelotide base pairs (TTAGGG – AATCCC), and SNP’s (single nucleotide polymorphism) complicated we human beings are!
Remember the nasty free radical? Free radicals damage telomeres, just like a worn out shoelace. Due to an array of environmental factors discussed in Part 1. Continued insult to one’s telomeres can result in the reduction of the enzyme telomerase. Secondly, telomere length does naturally decline with age (2). However, Lastly: telomere length predicts mortality (3) meaning, how well you sleep, what you put in your mouth, exposure to carcinogens, psychological stress, and how much you move (Part 3), determines the length of your telemeres (3).
Want to learn more before part 3? Watch the following TED talk by the Nobel laureate Dr. Elizabeth Blackburn.
So many “T’s” not including the nucleotide Thymine to take in peeps (excuse the alliteration). And a tricky topic to simplify!
I encourage you to follow up on the links, and take a healthy interest!
Stay tuned for Part 3: where I discuss: what form(s) of exercise is best for your telomeres!
1. BLACKBURN, E. H. AND EPEL, E. The telomere effect In-text: (Blackburn and Epel, n.d.)
2. Baker, D. J., et al., “Clearance of p16Ink4a-positive Senescent Cells Delays Ageing- Associated Disorders.” Nature 479, no. 7372 (November 2, 2011): 232-36, doi:10.1038/nature10600.
3. Rode, L., B. G. Nordestgaard, snd S. E. Bojesen, “Peripheral Blood Leukocyte Telomere Length and Mortality Among 64, 637 Individuals from the General Population.” Journal of the National Cancer Institute107, no. 6 (May 2015): djv074, doi:10.1093/jnci/djv074.